EEGBrain Surgery

Discover cortiQ 2.0: State-of-the-Art Cortical Mapping for Advanced Epilepsy and Tumour Surgery

cortiQ 2.0 improves the accuracy of brain mapping in epilepsy and brain tumour surgery using electrocorticographic (ECoG) data and advanced high-gamma mapping. By identifying the critical brain areas responsible for essential functions such as motor movement and speech production, this state-of-the-art neurotechnology system enables safer resections and significantly reduces the risk of neurological deficits.

December 20243 min readECoG & BCIEpilepsy & Tumour

cortiQ 2.0 — the cortical mapping interface with stereo-EEG and ECoG

Designed to optimise both patient outcomes and surgical efficiency, cortiQ 2.0 minimises mapping time while improving accuracy, reduces afterdischarges, lowers seizure activity and makes procedures safer. Its ability to identify functional regions precisely allows critical brain areas to be better preserved and contributes to post-operative quality of life. For brain tumour patients, this advanced approach improves survival rates by making it possible to distinguish accurately between tumour margins and healthy tissue.

Key Features

cortiQ 2.0 sets a new standard in cortical mapping. By integrating neurotechnology and clinical practice in a unique way, it gives surgeons unmatched safety, precision and efficiency even in the most complex procedures.

High-Gamma Mapping (CQ): Key brain regions are identified through high-gamma mapping with ECoG or stereo-EEG using the advanced CQ module.
White Matter Exploration: Cortical mapping in the white matter for a deeper understanding of connectivity and function within the brain’s communication pathways.
Electrical Stimulation (ECS): The ability to stimulate identified regions at up to 15 mA with the ECS module to verify functional areas.
Cortico-Cortical Evoked Potentials (CCEP): Efficient mapping of brain networks by stimulating electrode pairs without artefacts.
Somatosensory Evoked Potentials (SEP): Rapid identification of the central sulcus for more precise surgical planning.
High-Fidelity Evoked Potentials: Stimulation artefacts minimised with a DC-coupled amplifier.
Accurate Montage: Set up 2D recordings quickly, use the 3D Montage Creator for localisation, or import existing coordinates.
Impedance Measurement: Frequency-dependent impedance analysis for a better understanding of the electrode–tissue interface.

Advanced Features

cortiQ 2.0 brings pioneering brain mapping capabilities to neuroscience, offering unmatched tools for real-time analysis, multi-site mapping and integration with imaging data:

Import imaging files (*.VTK, *.NIFTI, *.STL) and use data such as DTI to see how the maps connect through the white matter.
Observe high-gamma activity in real time and map several locations simultaneously while the patient performs a task.
Areas related to a perception task can be localised without the patient having to report stimulation symptoms.
Extend your IOM language mapping with high-gamma activity maps, including white matter, and the related evoked potentials.
The DC-coupled amplifier records evoked potentials without filter artefacts, allowing precise interpretation of the early components of cortico-cortical evoked potentials.
Signal quality control helps the user verify the EEG during set-up.
Optimise the value of your recordings in offline analysis with EEG synchronised to stimulus information and external devices (TTL).

Integrated Neuromodulation Applications

Combine cortiQ 2.0 with g.HIsys Professional, the rapid prototyping environment for a wide range of neural recording and stimulation. The software provides the amplification and signal processing functionality needed for precise neural procedures.

g.HIamp Multichannel Amplifier: 24 bit, 80–256 channels and 38.4 kHz for comprehensive neural recordings.
g.Estim PRO: Provides controlled electrical stimulation for targeted neural modulation.
g.Estim PRO Switching Unit: Seamless sensing, switching and stimulation of specific brain regions across 256 channels.

Why cortiQ 2.0 for Advanced Brain Mapping?

Enhanced Surgical Precision: Accurately localise and preserve the eloquent cortex; critical regions stay unharmed during procedures.
Enhanced Patient Safety: By minimising neurological deficits, the system puts patient recovery and long-term quality of life first.
Time Efficiency: Significantly shortens mapping time, delivering faster and more effective procedures without compromising accuracy.
Cutting-Edge Neurotechnology: Lead neuroscience and clinical innovation with the latest advances in brain mapping and neuromodulation.
MATLAB/Simulink Closed Loop: Define and customise stimulation protocols seamlessly; trigger responses within just a few milliseconds.
Multi-Site Stimulation: Switch effortlessly between stimulation sites or combine several stimulators for parallel activation.